Return to Main PageBolten W, Glade M, Raum S, et al. Arthritis. 2015. Systemic enzymes in adults with moderate-to-severe knee osteoarthritis showed improvement in pain scores (Lequesne Functional Index) and total WOMAC scores similar to NSAID (diclofenac).Please enter your email address to gain access. I am a practitioner Don't miss out on exclusive webinars, news, and promotions. Add me to your email list We value your privacy and would never spam you. Submit